C16, PKR inhibitor (ab144595)
Key features and details
- Specific PKR inhibitor
- CAS Number: 608512-97-6
- Purity: > 98%
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
C16, PKR inhibitor -
Description
Specific PKR inhibitor -
Biological description
Specific double-stranded RNA-dependent protein kinase (PKR) inhibitor. Prevents PKR-induced neuronal loss in vivo. Inhibits apoptotic PKR/eIF2α signaling pathway in vivo. Neuroprotective, antitumor and anti-inflammatory agent. Active in vivo and in vitro. -
Purity
> 98% -
CAS Number
608512-97-6 -
Chemical structure
Properties
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Chemical name
6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one -
Molecular weight
268.30 -
Molecular formula
C13H8N4OS -
PubChem identifier
67016828 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC2=C(C3=C1NC(=O)C3=CC4=CN=CN4)SC=N2 -
Source
Synthetic
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Research areas