Quinol 1h, Antitumor agent (ab144639)
Key features and details
- Potent, selective antitumor agent
- CAS Number: 840474-95-5
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Quinol 1h, Antitumor agent -
Description
Potent, selective antitumor agent -
Biological description
Potent, selective antitumor agent. Antitumor activity observed in HCT 116 (GI50 = 40 nM) and HT 29 (GI50 = 380 nM), and in breast cancer cell lines. Potent inhibitory effect in NCI 60 cells (GI50 =16 nM and LC50 = 2.24 µM). Active in vitro.
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Purity
> 99% -
General notes
Sold under license from CRT -
CAS Number
840474-95-5 -
Chemical structure
Properties
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Chemical name
4-[1-(Benzenesulfonyl)-6-fluoro-1H-indol-2-yl]-4-hydroxycyclohexa-2,5-dien-1-one -
Molecular weight
383.39 -
Molecular formula
C20H14FNO4S -
PubChem identifier
9907134 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(C=C1)C=CC1(O)C2=CC3=C(N2S(=O)(C4=CC=CC=C4)=O)C=CC=C3 -
Source
Synthetic
