Brivudine, pyrimidine nucleoside analog (ab143368)
Key features and details
- Pyrimidine nucleoside analog. Antiviral agent.
- CAS Number: 69304-47-8
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Brivudine, pyrimidine nucleoside analog -
Description
Pyrimidine nucleoside analog. Antiviral agent. -
Biological description
Pyrimidine nucleoside analog. Antiviral agent (IC50 values are 76 nM and 1.4 μM for herpesvirus and HIV respectively). Blocks DNA polymerase. Binds to heat shock protein HSPB1 and inhibits interaction with its binding partners. Shows anticancer effects in vivo. Orally active. -
CAS Number
69304-47-8 -
Chemical structure
Properties
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Chemical name
5-(2-Bromoethenyl)-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione -
Molecular weight
333.13 -
Molecular formula
C11H13BrN2O5 -
PubChem identifier
3183 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1C(C(OC1N2C=C(C(=O)NC2=O)C=CBr)CO)O -
Source
Synthetic
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Research areas