Parthenolide, Anti-inflammatory agent (ab120849)
Key features and details
- Lactone derived from Tanacetum parthenium. Anti-inflammatory agent.
- CAS Number: 20554-84-1
- Purity: > 95%
- Soluble in DMSO to 100 mM and in ethanol to 75 mM
- Form / State: Solid
- Source: Tanacetum parthenium
Overview
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Product name
Parthenolide, Anti-inflammatory agent -
Description
Lactone derived from Tanacetum parthenium. Anti-inflammatory agent. -
Biological description
Lactone derived from Tanacetum parthenium. Anti-inflammatory agent. Inhibits NF-κB indirectly by inhibiting IκB and directly by modifying p65. Additionally induces apoptosis and shows antitumor and antiangiogenic effects. Active in vivo. -
Purity
> 95% -
CAS Number
20554-84-1 -
Chemical structure
Properties
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Chemical name
(1aR,4E,7aS,10aS,10bR)-2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methylene-oxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one -
Molecular weight
248.32 -
Molecular formula
C15H20O3 -
PubChem identifier
6473881 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 75 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=CCCC2(C(O2)C3C(CC1)C(=C)C(=O)O3)C -
Source
Tanacetum parthenium
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Research areas
