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Immunology Adaptive Immunity T Cells Cytotoxic Cells

Biotin Anti-CD8 alpha antibody [53-6.7] (ab25176)

Biotin Anti-CD8 alpha antibody [53-6.7] (ab25176)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Biotin Rat monoclonal [53-6.7] to CD8 alpha
  • Suitable for: Flow Cyt
  • Reacts with: Mouse
  • Conjugation: Biotin
  • Isotype: IgG2a

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Overview

  • Product name

    Biotin Anti-CD8 alpha antibody [53-6.7]
    See all CD8 alpha primary antibodies
  • Description

    Biotin Rat monoclonal [53-6.7] to CD8 alpha
  • Host species

    Rat
  • Conjugation

    Biotin
  • Specificity

    ab25176 recognises a chain of the murine CD8 heterodimer, Mr 32-34 kDa.
  • Tested Applications & Species

    Application Species
    Flow Cyt
    Mouse
    See all applications and species data
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • General notes


    In vivo and in vitro treatment with ab25176 effectively depletes CD8 alpha+ cells. ab25176 also blocks allogeneic help specific for class I MHC antigens and T cell responses to IL-2.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at +4°C. Avoid freeze / thaw cycle. Do Not Freeze.
  • Storage buffer

    pH: 7.20
    Preservative: 0.09% Sodium azide
    Constituents: 0.16% Sodium phosphate, 0.87% Sodium chloride
  • Concentration information loading...
  • Purity

    Affinity purified
  • Primary antibody notes

    In vivo and in vitro treatment with ab25176 effectively depletes CD8 alpha+ cells. ab25176 also blocks allogeneic help specific for class I MHC antigens and T cell responses to IL-2.
  • Clonality

    Monoclonal
  • Clone number

    53-6.7
  • Isotype

    IgG2a
  • Light chain type

    kappa
  • Research areas

    • Immunology
    • Adaptive Immunity
    • T Cells
    • Cytotoxic Cells
    • Immunology
    • Adaptive Immunity
    • T Cells
    • CD
    • Immunology
    • Adaptive Immunity
    • MHC
    • Class I
    • Cancer
    • Tumor immunology
    • CD markers

Images

  • Flow Cytometry - Biotin Anti-CD8 alpha antibody [53-6.7] (ab25176)
    Flow Cytometry - Biotin Anti-CD8 alpha antibody [53-6.7] (ab25176)

     

     

    Flow cytometry analysis showing C57Bl/6 splenocytes stained with ab25176 (solid line). Isotype control antibody was Rat Ig2a Biotin (dashed line).

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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