Binimetinib, MEK1/2 inhibitor (ab254449)
Key features and details
- Potent and selective allosteric inhibitor of MEK1/2
- CAS Number: 606143-89-9
- Purity: > 99%
Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Binimetinib, MEK1/2 inhibitor -
Description
Potent and selective allosteric inhibitor of MEK1/2 -
Alternative names
- ARRY-162
- ARRY-438162
- ARRY162
see all -
Biological description
Potent and selective allosteric inhibitor of MEK1/2. Orally bioavailable.
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Purity
> 99% -
General notes
Solutions in DMSO may be stored at -20°C for up to 3 months.
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CAS Number
606143-89-9 -
Chemical structure
Properties
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Chemical name
6-(4-Bromo-2-fluoroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide
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Molecular weight
441.23 -
Molecular formula
C17H15BrF2N4O3 -
PubChem identifier
10288191 -
Storage instructions
Shipped at Room Temperature. Store at -20°C long term. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO to 50 mM
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Handling
Refer to SDS for more information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)F)C(=O)NOCCO -
Source
Synthetic
