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Binimetinib, MEK1/2 inhibitor (ab254449)

Key features and details

  • Potent and selective allosteric inhibitor of MEK1/2
  • CAS Number: 606143-89-9
  • Purity: > 99%

  • Soluble in DMSO to 50 mM

  • Form / State: Solid
  • Source: Synthetic

Overview

  • Product name

    Binimetinib, MEK1/2 inhibitor

  • Description

    Potent and selective allosteric inhibitor of MEK1/2

  • Alternative names

    • ARRY-162
    • ARRY-438162
    • ARRY162
    • ARRY438162
    • MEK162
    see all

  • Biological description

    Potent and selective allosteric inhibitor of MEK1/2. Orally bioavailable.

  • Purity

    > 99%

  • General notes

    Solutions in DMSO may be stored at -20°C for up to 3 months.

  • CAS Number

    606143-89-9

  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    6-(4-Bromo-2-fluoroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide

  • Molecular weight

    441.23

  • Molecular formula

    C17H15BrF2N4O3

  • PubChem identifier

    10288191

  • Storage instructions

    Shipped at Room Temperature. Store at -20°C long term. Store under desiccating conditions.

  • Solubility overview

    Soluble in DMSO to 50 mM

  • Handling

    Refer to SDS for more information.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)F)C(=O)NOCCO

  • Source

    Synthetic

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