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Signal Transduction Cytoskeleton / ECM Extracellular Matrix ECM Enzymes MMP

Batimastat (BB-94), Matrix metalloprotease (MMP) inhibitor (ab142087)

Price and availability

264 681 ₸

Availability

Order now and get it on Thursday February 25, 2021

Key features and details

  • Potent, broad-spectrum MMP inhibitor
  • CAS Number: 130370-60-4
  • Purity: > 98%
  • Soluble in DMSO to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Batimastat (BB-94), Matrix metalloprotease (MMP) inhibitor
  • Description

    Potent, broad-spectrum MMP inhibitor
  • Biological description

    Potent, broad-spectrum MMP inhibitor (IC50 values are 3 (MMP-1), 4 (MMP-2), 4 (MMP-9), 6 (MMP-7), 20 nM (MMP-3)). Anticancer activity in vivo.

  • Purity

    > 98%
  • CAS Number

    130370-60-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2R,3S)-N4-Hydroxy-N1-[(1S)-2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]butanediamide
  • Molecular weight

    477.64
  • Molecular formula

    C23H31N3O4S2
  • PubChem identifier

    5362422
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(C)CC(C(CSC1=CC=CS1)C(=O)NO)C(=O)NC(CC2=CC=CC=C2)C(=O)NC
  • Source

    Synthetic

  • Research areas

    • Cardiovascular
    • Angiogenesis
    • Adhesion / ECM
    • Matrix Metalloproteinases
    • MMP
    • Signal Transduction
    • Cytoskeleton / ECM
    • Extracellular Matrix
    • ECM Enzymes
    • MMP
    • Cancer
    • Invasion/microenvironment
    • Angiogenesis
    • ECM enzymes
    • MMPs
    • Cancer
    • Invasion/microenvironment
    • ECM
    • Extracellular matrix
    • MMPs
    • Cell Biology
    • Proteolysis / Ubiquitin
    • Proteolytic enzymes
    • Metalloprotease
    • MMPs
    • Cancer
    • Tumor biomarkers
    • Enzymes
    • MMPs
    • Cardiovascular
    • Atherosclerosis
    • Thrombosis
    • Endothelial mediators/regulators
    • Cardiovascular
    • Atherosclerosis
    • Thrombosis
    • Other
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    • Matrix metalloprotease
    • Inhibitors
    • Biochemicals
    • Pharmacology
    • Signaling
    • Extracellular matrix & cell adhesion
    • Matrix metalloprotease

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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