AZD8330, MEK inhibitor (ab235504)
Key features and details
- A selective allosteric MEK inhibitor
- CAS Number: 869357-68-6
- Purity: > 98%
Soluble in DMSO to 199.46 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
AZD8330, MEK inhibitor -
Description
A selective allosteric MEK inhibitor -
Alternative names
- 2-((2-fluoro-4-iodophenyl)amino)-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide
- ARRY-424704
- ARRY-704
see all -
Biological description
A selective allosteric MEK inhibitor. Orally active. IC50 of 7 nM.
-
Purity
> 98% -
General notes
Protect from air and light.
-
CAS Number
869357-68-6 -
Chemical structure
Properties
-
Molecular weight
461.23 -
Molecular formula
C16H17FIN3O4 -
Sequence
2-((2-fluoro-4-iodophenyl)amino)-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide -
PubChem identifier
16666708 -
Storage instructions
Shipped at 4°C. Store at -20°C long term. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO to 199.46 mM
-
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
CC1=CC(=C(N(C1=O)C)NC2=C(C=C(C=C2)I)F)C(=O)NOCCO -
Source
Synthetic
-
Research areas
