Auranofin, inhibits both leukocyte activation pathways (ab141509)
Key features and details
- Organic gold compound. Anti-inflammatory and antiproliferative agent.
- CAS Number: 34031-32-8
- Purity: > 98%
- Soluble in DMSO to 100 mM and ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Auranofin, inhibits both leukocyte activation pathways -
Description
Organic gold compound. Anti-inflammatory and antiproliferative agent. -
Biological description
Organic gold compound. Anti-inflammatory and antiproliferative agent. Glutathione S-transferase P1-1 inhibitor (IC50 = 33 μM). Shows antiproliferative effects through STAT3 inhibition. Shows anti-inflammatory effects in vivo. Orally active.
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Purity
> 98% -
CAS Number
34031-32-8 -
Chemical structure
Properties
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Chemical name
[1-(Thio-κS)-β-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)gold -
Molecular weight
678.48 -
Molecular formula
C20H34AuO9PS -
PubChem identifier
24199313 -
Storage instructions
Store at Room Temperature. It is important to note that this product is reported to be light sensitive. Store In the Dark. -
Solubility overview
Soluble in DMSO to 100 mM and ethanol to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCP(CC)CC.CC(=O)OCC1C(C(C(C(O1)[S-])OC(=O)C)OC(=O)C)OC(=O)C.[Au+] -
Source
Synthetic
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Research areas
