Aconitine, Voltage-gated Na+ channel activator (ab142475)
Key features and details
- Voltage-gated Na+ channel activator
- CAS Number: 302-27-2
- Purity: > 88%
- Soluble in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
Aconitine, Voltage-gated Na+ channel activator -
Description
Voltage-gated Na+ channel activator -
Biological description
Voltage-gated Na+ channel activator. Binds to neurotoxin binding site 2 of the Na+ channel α-subunit. Shows arrhythmogenic effects in vivo. Orally active. -
Purity
> 88% -
CAS Number
302-27-2 -
Chemical structure
Properties
-
Chemical name
(1α,3α,6α,14α,16β)-8-(Acetyloxy)-20-ethyl-3,13,15-trihydroxy-1,6,16-trimethoxy-4-(methoxymethyl)aconitan-14-yl benzoate -
Molecular weight
645.74 -
Molecular formula
C34H47NO11 -
PubChem identifier
2012 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
CCN1CC2(C(CC(C34C2C(C(C31)C5(C6C4CC(C6OC(=O)C7=CC=CC=C7)(C(C5O)OC)O)OC(=O)C)OC)OC)O)COC -
Source
Synthetic
-
Research areas
