Mizoribine hydrobromide, inosine monophosphate dehydrogenase inhibitor (ab143415)
Key features and details
- Potent, selective inosine monophosphate dehydrogenase inhibitor
- CAS Number: 50924-49-7
- Purity: > 98%
- Soluble in water to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Mizoribine hydrobromide, inosine monophosphate dehydrogenase inhibitor -
Description
Potent, selective inosine monophosphate dehydrogenase inhibitor -
Biological description
Potent and selective inosine monophosphate dehydrogenase inhibitor (IC50 = 4 nM) Blocks T and B lymphocyte proliferation. Attenuates MCP-1 expression. Shows immunosuppressant effects in vivo. -
Purity
> 98% -
CAS Number
50924-49-7 -
Chemical structure
Properties
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Chemical name
1-[3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxyimidazole-4-carboxamide hydrobromide -
Molecular weight
340.13 -
Molecular formula
C9H14BrN3O6 -
PubChem identifier
71434259 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=NC(=C(N1C2C(C(C(O2)CO)O)O)O)C(=O)N.Br -
Source
Synthetic
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Research areas
