Antibodies, Proteins, Kits and Reagents for Life Science

288 134 ₸ Product size

100 µg 288 134 ₸ 100 µg 288 134 ₸

Order now and get it on Thursday February 25, 2021

Key features and details

Product name

Anti-Syntaxin 16 antibody - Drosophila Golgi/Trans-Golgi Marker
See all Syntaxin 16 primary antibodies
Description

Rabbit polyclonal to Syntaxin 16 - Drosophila Golgi/Trans-Golgi Marker
Host species

Rabbit
Tested Applications & Species

Application Species
WB
Drosophila melanogaster

See all applications and species data
Immunogen

Synthetic peptide corresponding to Drosophila melanogaster Syntaxin 16 aa 200-300 conjugated to keyhole limpet haemocyanin.
(Peptide available as ab32339)

Form

Liquid
Storage instructions

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage buffer

pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS

Batches of this product that have a concentration
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Purity

Immunogen affinity purified
Clonality

Polyclonal
Isotype

IgG
Research areas

Our Abpromise guarantee covers the use of ab32340 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Guaranteed

Tested applications are guaranteed to work and covered by our Abpromise guarantee.

Predicted

Predicted to work for this combination of applications and species but not guaranteed.

Incompatible

Does not work for this combination of applications and species.

Application	Species
WB	Drosophila melanogaster

Application	Abreviews	Notes
WB		Use a concentration of 2.5 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa).

Notes
WB Use a concentration of 2.5 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa).

Application notes

Is unsuitable for ICC/IF.

Function

SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.
Tissue specificity

Ubiquitous.
Involvement in disease

Genetic variations in STX16 may be a cause of pseudohypoparathyroidism type 1B (PHP1B) [MIM:603233]. Pseudohypoparathyroidism refers to a heterogeneous group of disorders characterized by resistance to parathyroid hormone (PTH). PHP1B is characterized by PTH-resistant hypocalcemia and hyperphosphatemia. Patients affected with PHP1B lack developmental defects characteristic of Albright hereditary osteodystrophy, and typically show no other endocrine abnormalities besides resistance to PTH. In some cases microdeletions involving STX16 appear to cause loss of methylation at exon A/B of the GNAS gene, resulting in PHP1B.
Sequence similarities

Belongs to the syntaxin family.
Contains 1 t-SNARE coiled-coil homology domain.
Cellular localization

Cytoplasm and Golgi apparatus membrane.
Target information above from: UniProt accession O14662 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
Alternative names
- hsyn16 antibody
- MGC90328 antibody
- Stx16 antibody
- STX16_HUMAN antibody
- Syn16 antibody
- Syntaxin-16 antibody
see all

Publishing research using ab32340? Please let us know so that we can cite the reference in this datasheet.

ab32340 has been referenced in 4 publications.

Bellec K et al. Stratum recruits Rab8 at Golgi exit sites to regulate the basolateral sorting of Notch and Sanpodo. Development 145:N/A (2018). PubMed: 29967125
Charng WL et al. Drosophila Tempura, a novel protein prenyltransferase a subunit, regulates notch signaling via Rab1 and Rab11. PLoS Biol 12:e1001777 (2014). ICC/IF ; Drosophila melanogaster . PubMed: 24492843
Hornbruch-Freitag C et al. Drosophila Swiprosin-1/EFHD2 accumulates at the prefusion complex stage during Drosophila myoblast fusion. J Cell Sci 124:3266-78 (2011). ICC/IF ; Drosophila melanogaster . PubMed: 21896648
Tiklová K et al. Epithelial septate junction assembly relies on melanotransferrin iron binding and endocytosis in Drosophila. Nat Cell Biol 12:1071-7 (2010). WB, IHC-P ; Drosophila melanogaster . PubMed: 20935638