Anti-NFkB p105 / p50 antibody (ab7549)
Key features and details
- Rabbit polyclonal to NFkB p105 / p50
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-NFkB p105 / p50 antibody
See all NFkB p105 / p50 primary antibodies -
Description
Rabbit polyclonal to NFkB p105 / p50 -
Host species
Rabbit -
Specificity
Recognition is at the N-terminus. This antibody will "supershift " NFkB complexes containing the human p50 subunit. Control peptide ab7550 will compete only with the specific reaction of antiserum with Human NFkB p50 (NFKB1). -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide:
AEDDPYLGRFEQMF
conjugated to KLH, corresponding to N terminal amino acids 2-15 of Human NFkB p50. -
Positive control
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General notes
NFkB is formed as a homo- or hetero-dimer. Subunits include p50 (NFkB1), p65 (RelA), c-Rel, RelB and p52 (NFkB2). The classic NFkB form exists as a p50-p65 heterodimer and predominates in many cell types. Many of the possible combinatorial forms of homo- and heterodimers have been identified and growing evidence indicates that different forms of NFkB have different functions in cells. Nuclear translocation of NFkB is confirmed by the use of electrophorectic mobility shift assays or by immunoblotting with nuclear extracts. The subunit composition of NFkB is confirmed by the use of antibodies that "supershift" the DNA/protein complex.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.01% Sodium azide -
Concentration information loading... -
Purity
Whole antiserum -
Purification notes
This product was prepared from monospecific antiserum by delipidation and defibrination. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
