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Signal Transduction Signaling Pathway G Protein Signaling Small G Proteins Other

Oxamflatin, HDAC inhibitor (ab144507)

Key features and details

  • Potent mammalian HDAC inhibitor
  • CAS Number: 934986-71-7
  • Purity: > 95%
  • Soluble in DMSO to 25 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Oxamflatin, HDAC inhibitor
  • Description

    Potent mammalian HDAC inhibitor
  • Biological description

    Potent mammalian HDAC inhibitor (IC50 = 15.7 nM). Induces an elongated cell shape morphology with filamentous protrusions. Shows antiproliferative effects. Shows antitumor effects in vivo.
  • Purity

    > 95%
  • CAS Number

    934986-71-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (E)-5-[3-(Benzenesulfonamido)phenyl]-N-hydroxypent-2-en-4-ynamide
  • Molecular weight

    342.37
  • Molecular formula

    C17H14N2O4S
  • PubChem identifier

    5353852
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 25 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC(=C2)C#C/C=C/C(=O)NO
  • Source

    Synthetic

  • Research areas

    • Cardiovascular
    • Angiogenesis
    • Cytokines
    • Other
    • Immunology
    • Adaptive Immunity
    • MHC
    • Class I
    • Immunology
    • Innate Immunity
    • Cytokines
    • Interferons
    • Cancer
    • Tumor immunology
    • Cytokines
    • Interferons

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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