Anti-Myosin VIIa/MYO7A antibody (ab92996)
Key features and details
- Rabbit polyclonal to Myosin VIIa/MYO7A
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-Myosin VIIa/MYO7A antibody
See all Myosin VIIa/MYO7A primary antibodies -
Description
Rabbit polyclonal to Myosin VIIa/MYO7A -
Host species
Rabbit -
Tested Applications & Species
See all applications and species dataApplication Species WB Mouse
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Immunogen
Synthetic peptide corresponding to Mouse Myosin VIIa/MYO7A aa 1000-1100 conjugated to keyhole limpet haemocyanin.
(Peptide available asab104961) -
Positive control
- This antibody gave a positive signal in mouse testis tissue lysate.
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General notes
This product was previously labelled as Myosin VIIa
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration
Concentration information loading...Purity
Immunogen affinity purifiedClonality
PolyclonalIsotype
IgGResearch areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab92996 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
GuaranteedTested applications are guaranteed to work and covered by our Abpromise guarantee.
PredictedPredicted to work for this combination of applications and species but not guaranteed.
IncompatibleDoes not work for this combination of applications and species.
Application Species WB MouseAll applications RatHumanPigApplication Abreviews Notes WB Use a concentration of 1 µg/ml. Detects a band of approximately 238 kDa (predicted molecular weight: 255 kDa).Notes WB
Use a concentration of 1 µg/ml. Detects a band of approximately 238 kDa (predicted molecular weight: 255 kDa).Target
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Relevance
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. In retina, myosin VIIa may play a role in trafficking of ribbon-synaptic vesicle complexes and renewal of the outer photoreceptors disks. In inner ear, it may maintain the rigidity of stereocilia during the dynamic movements of the bundle. -
Cellular localization
Cytoplasmic, cytoskeleton -
Database links
- Entrez Gene: 4647 Human
- Entrez Gene: 17921 Mouse
- Entrez Gene: 397373 Pig
- Entrez Gene: 266714 Rat
- Omim: 276903 Human
- SwissProt: Q13402 Human
- SwissProt: P97479 Mouse
- Unigene: 370421 Human
see all -
Alternative names
- Deafness autosomal dominant 11 antibody
- Deafness autosomal recessive 2 antibody
- DFNA11 antibody
see all
Images
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Western blot - Anti-Myosin VIIa/MYO7A antibody (ab92996)Anti-Myosin VIIa/MYO7A antibody (ab92996) at 1 µg/ml + Testis (Mouse) Tissue Lysate at 10 µg
Secondary
Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 255 kDa
Observed band size: 238 kDa why is the actual band size different from the predicted?
Additional bands at: 50 kDa, 60 kDa. We are unsure as to the identity of these extra bands.
Exposure time: 12 minutes
Datasheets and documents
References (0)
ab92996 has not yet been referenced specifically in any publications.
Images
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Western blot - Anti-Myosin VIIa/MYO7A antibody (ab92996)Anti-Myosin VIIa/MYO7A antibody (ab92996) at 1 µg/ml + Testis (Mouse) Tissue Lysate at 10 µg
Secondary
Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 255 kDa
Observed band size: 238 kDa why is the actual band size different from the predicted?
Additional bands at: 50 kDa, 60 kDa. We are unsure as to the identity of these extra bands.
Exposure time: 12 minutes
