Anti-C3 antibody [8G4] (ab17455)
Key features and details
- Mouse monoclonal [8G4] to C3
- Reacts with: Human
- Isotype: IgG2a
Overview
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Product name
Anti-C3 antibody [8G4]
See all C3 primary antibodies -
Description
Mouse monoclonal [8G4] to C3 -
Host species
Mouse -
Specificity
Ab17455 is specific for an allotypic marker on human C3 (Leu instead of Pro in codon 314 of exon 9), which occurs regularly in the beta-chain of C3F and occasionally in the beta-chain of C3S. F and S mean fast and slow, respectively, on agarose gel electrophoresis. Ab17455 reacts with the 75-kDa beta-chain band on SDS-PAGE immunoblotting of reduced C3, and reacts with 20-kDa and 17-kDa beta-chain fragments produced by cyanogen bromide cleavage. -
Species reactivity
Reacts with: Human -
Immunogen
Full length native C3 protein isolated from human plasma.
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Epitope
The exact epitope is not known, but the antibody is specific for the allotypic human C3 where Leu is found instead of Pro in codon 314 of exon 9.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Constituents: 0.0268% PBS, 2.9% Sodium chloride -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
8G4 -
Myeloma
x63-Ag8.653 -
Isotype
IgG2a -
Light chain type
kappa -
Research areas