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Immunology Innate Immunity Complement Classical Pathway

Anti-C3 antibody [8G4] (ab17455)

Price and availability

278 083 ₸

Availability

Order now and get it on Thursday February 25, 2021

Key features and details

  • Mouse monoclonal [8G4] to C3
  • Reacts with: Human
  • Isotype: IgG2a

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Overview

  • Product name

    Anti-C3 antibody [8G4]
    See all C3 primary antibodies
  • Description

    Mouse monoclonal [8G4] to C3
  • Host species

    Mouse
  • Specificity

    Ab17455 is specific for an allotypic marker on human C3 (Leu instead of Pro in codon 314 of exon 9), which occurs regularly in the beta-chain of C3F and occasionally in the beta-chain of C3S. F and S mean fast and slow, respectively, on agarose gel electrophoresis. Ab17455 reacts with the 75-kDa beta-chain band on SDS-PAGE immunoblotting of reduced C3, and reacts with 20-kDa and 17-kDa beta-chain fragments produced by cyanogen bromide cleavage.
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Full length native C3 protein isolated from human plasma.

  • Epitope

    The exact epitope is not known, but the antibody is specific for the allotypic human C3 where Leu is found instead of Pro in codon 314 of exon 9.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.40
    Constituents: 0.0268% PBS, 2.9% Sodium chloride
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Monoclonal
  • Clone number

    8G4
  • Myeloma

    x63-Ag8.653
  • Isotype

    IgG2a
  • Light chain type

    kappa
  • Research areas

    • Immunology
    • Innate Immunity
    • Complement
    • Classical Pathway
    • Neuroscience
    • Cell Type Marker
    • Neuron marker
    • Synapse marker

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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