Anti-C1q antibody [4.8] (ab182451)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [4.8] to C1q
- Suitable for: IHC-FoFr
- Knockout validated
- Reacts with: Mouse
Overview
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Product name
Anti-C1q antibody [4.8]
See all C1q primary antibodies -
Description
Rabbit monoclonal [4.8] to C1q -
Host species
Rabbit -
Tested Applications & Species
See all applications and species dataApplication Species IHC-FoFr Mouse -
Immunogen
Full length native protein (purified) corresponding to Mouse C1q.
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Positive control
- IHC: Mouse brain tissue (adult) .
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General notes
This antibody was developed as part of a collaboration between Abcam and the lab of Ben A. Barres at Stanford University:
Alexander H. Stephan et al. , A Dramatic Increase of C1q Protein in the CNS during Normal Aging ,The Journal of Neuroscience.
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.2
Preservative: 0.01% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
4.8 -
Isotype
IgG -
Research areas
Images
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ab182451 (1/500) staining C1q in 15µm coronal brain sections from postnatal day 90 C1qA KO mice and WT litter-mates (Botto et al., 1998) by immunohistochemistry (IHC-Fr - frozen sections). Tissue was fixed with 4% paraformaldehyde and permeabilized with 0.3% Triton. An Alexa Flour-conjugated Goat anti-Mouse IgG polyclonal (1/500) was used as the secondary antibody. Positive staining on wild type (WT) mouse cerebral cortex, and no staining on knockout (KO) mouse cerebral cortex.
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