Astana Biomed Group, an authorized Abcam distributor in Central Asia

Anti-C1q antibody [4.8] - Low endotoxin, Azide free (ab227072)

Key features and details

  • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
  • Rabbit monoclonal [4.8] to C1q - Low endotoxin, Azide free
  • Suitable for: IHC-Fr
  • Knockout validated
  • Reacts with: Mouse

Overview

  • Product name

    Anti-C1q antibody [4.8] - Low endotoxin, Azide free
    See all C1q primary antibodies

  • Description

    Rabbit monoclonal [4.8] to C1q - Low endotoxin, Azide free

  • Host species

    Rabbit

  • Tested Applications & Species

    Application Species
    IHC-FoFr
    Mouse
    See all applications and species data

  • Immunogen

    Full length native protein (purified).

  • Positive control

    • IHC-Fr: Mouse brain tissue (adult) .

  • General notes

    ab227072 is a carrier-free antibody designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.

     

    Our Low endotoxin, azide-free formats have low endotoxin level (≤ 1 EU/ml, determined by the LAL assay) and are free from azide, to achieve consistent experimental results in functional assays.

    This antibody was developed as part of a collaboration between Abcam and the lab of Ben A. Barres at Stanford University: Alexander H. Stephan et al. , A Dramatic Increase of C1q Protein in the CNS during Normal Aging ,The Journal of Neuroscience.

    This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free production
    For more information see here.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

Properties

Images

  • Immunohistochemistry (Frozen sections) - Anti-C1q antibody [4.8] - Low endotoxin, Azide free (ab227072)
    Immunohistochemistry (Frozen sections) - Anti-C1q antibody [4.8] - Low endotoxin, Azide free (ab227072) This image is kindly provided by Dr. Daniel Wilton from Boston Children’s Hospital.

    Immunohistochemistry (Frozen sections) analysis of 15 µm coronal brain sections from postnatal day 90 C1qA knockout mice and wild-type litter-mates (Botto et al., 1998) labeling C1q with ab227072 at 1/500 dilution. Tissues fixed with 4% paraformaldehyde, and permeabilized using 0.3% triton. Goat anti-Mouse IgG H&L (Alexa Fluor® 594) at 1/500 dilution was used as the secondary antibody (red). Nuclei counterstained with DAPI (teal).

  • Anti-C1q antibody [4.8] - Low endotoxin, Azide free (ab227072)
    Anti-C1q antibody [4.8] - Low endotoxin, Azide free (ab227072)

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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