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Epigenetics and Nuclear Signaling Chromatin Modifying Enzymes Ubiquitylation

Anti-BRCA1 antibody [GLK-2] (ab17251)

Price and availability

284 784 ₸

Availability

Order now and get it on Thursday February 25, 2021

Key features and details

  • Mouse monoclonal [GLK-2] to BRCA1
  • Reacts with: Human
  • Isotype: IgM

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Overview

  • Product name

    Anti-BRCA1 antibody [GLK-2]
    See all BRCA1 primary antibodies
  • Description

    Mouse monoclonal [GLK-2] to BRCA1
  • Host species

    Mouse
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Cow, Dog, Chimpanzee, Rhesus monkey, Gorilla
  • Immunogen

    Synthetic peptide:

    LDSVALYQCQELDTYLIPQIPHSHY

    , corresponding to C terminal amino acids 1839-1863 of Human BRCA1.
    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive control

    • Ovarian carcinoma
  • General notes


    ab17251 stains 94% of ovarian carcinomas with a mutation in exon 11. However, staining is absent in 100% of tumors with mutations other than exon 11.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.05% Sodium azide
    Constituents: Tissue culture supernatant, 1% BSA
  • Concentration information loading...
  • Purity

    Tissue culture supernatant
  • Primary antibody notes

    ab17251 stains 94% of ovarian carcinomas with a mutation in exon 11. However, staining is absent in 100% of tumors with mutations other than exon 11.
  • Clonality

    Monoclonal
  • Clone number

    GLK-2
  • Isotype

    IgM
  • Research areas

    • Epigenetics and Nuclear Signaling
    • Chromatin Modifying Enzymes
    • Ubiquitylation
    • Epigenetics and Nuclear Signaling
    • DNA / RNA
    • DNA Damage & Repair
    • DNA Damage Response
    • BRCA1
    • Cell Biology
    • Proteolysis / Ubiquitin
    • Proteasome / Ubiquitin
    • Ubiquitin E3 Enzymes
    • RING Finger E3 Ligase
    • Epigenetics and Nuclear Signaling
    • Transcription
    • Cancer susceptibility
    • Tumor Suppressors
    • Cancer
    • Oncoproteins/suppressors
    • Tumor suppressors
    • Other

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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