Annexin V/ANXA5-Biotin Apoptosis Staining / Detection Reagent (ab14165)
Overview
-
Product name
Annexin V/ANXA5-Biotin Apoptosis Staining / Detection Reagent
See all Annexin V/ANXA5 reagents -
Tested applications
Suitable for: FM, Flow Cytmore details -
General notes
Note: For more detailed information view specific protocol.
Properties
-
Form
Liquid -
Storage instructions
Store at +4°C. Do not freeze. -
Storage buffer
Preservative: 0.02% Thimerosal (merthiolate)
Constituents: 0.05% Annexin V-Biotin, 1% BSA, PBS -
Concentration information loading... -
Research areas
-
Function
This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. -
Involvement in disease
Pregnancy loss, recurrent, 3 -
Sequence similarities
Belongs to the annexin family.
Contains 4 annexin repeats. -
Domain
The [IL]-x-C-x-x-[DE] motif is a proposed target motif for cysteine S-nitrosylation mediated by the iNOS-S100A8/A9 transnitrosylase complex.
A pair of annexin repeats may form one binding site for calcium and phospholipid. -
Post-translational
modificationsS-nitrosylation is induced by interferon-gamma and oxidatively-modified low-densitity lipoprotein (LDL(ox)) possibly implicating the iNOS-S100A8/9 transnitrosylase complex. - Information by UniProt
-
Alternative names
- Anchorin CII
- Annexin 5
- Annexin A5
see all
