AMI 1, protein arginine methyltransferase inhibitor (ab141472)
Key features and details
- Potent, selective and reversible protein arginine methyltransferase inhibitor
- CAS Number: 20324-87-2
- Purity: > 97%
- Soluble in water to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
AMI 1, protein arginine methyltransferase inhibitor -
Description
Potent, selective and reversible protein arginine methyltransferase inhibitor -
Biological description
Potent, selective and reversible protein arginine methyltransferase inhibitor (IC50 = 1.63 μM). ROS° scavenger with antioxidant effects (IC50 = 8.3 μM). Inhibits arginine in vitro without competing for the AdoMet binding site. Modulates nuclear receptor-regulated transcription in vivo. Cell-permeable.
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Purity
> 97% -
CAS Number
20324-87-2 -
Chemical structure
Properties
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Chemical name
7,7'-(Carbonyldiimino)bis[4-hydroxy2-naphthalenesulfonic acid] disodium salt -
Molecular weight
548.45 -
Molecular formula
C21H14N2Na2O9S2 -
PubChem identifier
88489 -
Storage instructions
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in water to 100 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC2=C(C=C(C=C2C=C1NC(=O)NC3=CC4=CC(=CC(=C4C=C3)O)S(=O)(=O)[O-])S(=O)(=O)[O-])O.[Na+].[Na+] -
Source
Synthetic
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Research areas
