A 438079, competitive P2X7 receptor antagonist (ab120413)
Key features and details
- Potent, competitive P2X7 receptor antagonist
- CAS Number: 899507-36-9
- Purity: > 98%
- Soluble in DMSO to 100 mM and in water to 5 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
A 438079, competitive P2X7 receptor antagonist -
Description
Potent, competitive P2X7 receptor antagonist -
Biological description
Potent, competitive P2X7 receptor antagonist (pIC50 = 6.5 nM). Shown to reduce pathological nociception.
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Purity
> 98% -
CAS Number
899507-36-9 -
Chemical structure
Properties
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Chemical name
3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine hydrochloride -
Molecular weight
342.61 -
Molecular formula
C13H9Cl2N5.HCl -
PubChem identifier
11688742 -
Storage instructions
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in water to 5 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.Clc3cccc(c2nnnn2Cc1cnccc1)c3Cl -
Source
Synthetic
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Research areas