BzATP triethylammonium salt, prototypic P2X7 agonist. P2 agonist. (ab120444)
Key features and details
- Potent, prototypic P2X7 agonist. P2 agonist.
- CAS Number: 112898-15-4
- Purity: > 94%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
BzATP triethylammonium salt, prototypic P2X7 agonist. P2 agonist. -
Description
Potent, prototypic P2X7 agonist. P2 agonist. -
Biological description
Prototypic P2X7 receptor agonist, showing 5-10 fold greater potency than ATP (pEC50 = 6.5). Also exhibits activity at other P2 receptors (EC50 values are 5 and 63 μM at P2X3 and P2Y11, respectively). Shows high potency at P2X1 receptor (pEC50 = 8.7). Potent activator of cAMP production.
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Purity
> 94% -
CAS Number
112898-15-4 -
Chemical structure
Properties
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Chemical name
2'(3')-O-(4-Benzoylbenzoyl)adenosine-5'-triphosphate triethylammonium salt -
Molecular weight
1018.97 -
Molecular formula
C24H24N5O15P3.3C6H15N -
PubChem identifier
71308559 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCN(CC)CC.C1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)C(=O)O[C@@H]3[C@H](O[C@H]([C@@H]3O)N4C=NC5=C(N=CN=C54)N)COP(=O)(O)OP(=O)(O)OP(=O)(O)O -
Source
Synthetic
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Research areas