NF023, competitive P2X1receptor antagonist (ab120454)
Key features and details
- Competitive P2X1 receptor antagonist
- CAS Number: 104869-31-0
- Purity: > 96%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
NF023, competitive P2X1receptor antagonist -
Description
Competitive P2X1 receptor antagonist -
Biological description
Suramin analog and subtype-selective competitive antagonist at P2X1 receptors (IC50 values are 0.21, 28.9, >50 and >100 μM for human P2X1, P2X3, P2X2, and P2X4-mediated responses, respectively). Inhibits contraction induced by electrical field stimulation in smooth muscle.
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Purity
> 96% -
CAS Number
104869-31-0 -
Chemical structure
Properties
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Chemical name
8,8'-[Carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt -
Molecular weight
1162.86 -
Molecular formula
C35H20N4Na6O21S6 -
PubChem identifier
4465 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=S(=O)(O[Na])c1cc(cc2c1c(ccc2S(=O)(=O)O[Na])NC(=O)c3cc(ccc3)NC(=O)Nc4cccc(c4)C(=O)Nc6ccc(c5cc(cc(c56)S(=O)(=O)O[Na])S(=O)(=O)O[Na])S(=O)(=O)O[Na])S(=O)(=O)O[Na] -
Source
Synthetic
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Research areas
