3-Cyano-7-ethoxycoumarin, Fluorogenic cytochrome P450 monooxygenase substrate (ab145344)
Key features and details
- Fluorogenic cytochrome P450 mixed-function monooxygenase substrate.
- CAS Number: 117620-77-6
- Purity: > 99%
- Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
3-Cyano-7-ethoxycoumarin, Fluorogenic cytochrome P450 monooxygenase substrate -
Description
Fluorogenic cytochrome P450 mixed-function monooxygenase substrate. -
Alternative names
- 7-Ethoxy-2-oxo-2H-1-benzopyran-3-carbonitrile
- 7-Ethoxycoumarin-3-carbonitrile
- CEC
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Biological description
Fluoreogenic cytochrome P450 mixed-function monooxygenase substrate. Metabolized to the fluorescent compound 3-cyano-7-hydroxycoumarin. About 50-100 times more sensitive than conventional substrate ethoxy-resorufin due to higher turn over rate.
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Purity
> 99% -
General notes
Fluorescence: λex 324 nm; λem 414 nm in DMSO.
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CAS Number
117620-77-6 -
Chemical structure
Properties
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Excitation
324nm -
Emission
414nm -
Molecular weight
215.20 -
Molecular formula
C12H9NO3 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
