AR 231453, GPR119 agonist (ab141627)
Key features and details
- Potent, selective GPR119 agonist
- CAS Number: 733750-99-7
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
AR 231453, GPR119 agonist -
Description
Potent, selective GPR119 agonist -
Biological description
Potent, selective G-protein coupled receptor 119 (GPR119) agonist (EC50 = 0.68 nM). Enhances glucose-induced insulin release. Antidiabetic activity. Orally active in vivo.
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Purity
> 99% -
CAS Number
733750-99-7 -
Chemical structure
Properties
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Chemical name
N-[2-Fluoro-4-(methylsulfonyl)phenyl]-5-nitro-6-[4-[3-(1-
methylethyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]-5-nitro-4-pyrimidinamine -
Molecular weight
505.50 -
Molecular formula
C21H24FN7O5S -
PubChem identifier
24939268 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)C1=NOC(=N1)C2CCN(CC2)C3=C(C(=NC=N3)NC4=C(C=C(C=C4)S(=O)(=O)C)F)[N+](=O)[O-] -
Source
Synthetic
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Research areas
