2-NBD-Glucose, Fluorescent glucose uptake probe (ab146200)
Key features and details
- Cell-permeable fluorescent glucose uptake probe
- CAS Number: 186689-07-6
- Soluble in ethanol to 50 mM and in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
2-NBD-Glucose, Fluorescent glucose uptake probe -
Description
Cell-permeable fluorescent glucose uptake probe -
Alternative names
- 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose
- 2-NBDG
- NBD-Glucose
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Biological description
Fluorescently-labeled deoxyglucose analog, used to directly monitor glucose uptake by living cells and tissues. Also used as a topical contrast reagent for the detection of neoplasia. Uptake can be monitored by real-time confocal, high-resolution or wide-field fluorescence microscopy and flow cytometry.
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CAS Number
186689-07-6 -
Chemical structure
Properties
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Excitation
465nm -
Emission
540nm -
Molecular weight
342.26 -
Molecular formula
C12H14N4O8 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 50 mM and in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
c1cc(c2c(c1N[C@@H]3[C@H]([C@@H]([C@H](OC3O)CO)O)O)non2)[N+](=O)[O-] -
Source
Synthetic