2-(N-Hexadecanoylamino)-4-nitrophenylphosphocholine hydroxide, Niemann-Pick disease indicator (ab144994)
Key features and details
- Indicator used in the detection and diagnosis of Niemann-Pick disease.
- CAS Number: 60438-73-5
- DMSO, water
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
2-(N-Hexadecanoylamino)-4-nitrophenylphosphocholine hydroxide, Niemann-Pick disease indicator -
Description
Indicator used in the detection and diagnosis of Niemann-Pick disease. -
Alternative names
- 2-[[Hydroxy[4-nitro-2-[(1-oxohexadecyl)amino]phenoxy]phosphinyl]oxy]-N,N,N-trimethyl-ethanaminium Hydroxide
- 2-Hexadecanoylamino-4-nitrophenylphosphorylcholine hyroxide
- HDA-PC
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Biological description
Indicator used in the detection and diagnosis of Niemann-Pick disease. Synthetic chromogenic analog of sphingomyelin which selectively measures the activity of acid sphingomyelinase (ASM). The production of ASM is inhibited in Niemann-Pick disease, allowing sphingomyelin to accumulate in the organs of affected persons.
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CAS Number
60438-73-5 -
Chemical structure
Properties
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Chemical name
2-[[Hydroxy[4-nitro-2-[(1-oxohexadecyl)amino]phenoxy]phosphinyl]oxy]-N,N,N-trimethylethanaminium hydroxide -
Molecular weight
575.67 -
Molecular formula
C27H50N3O8P -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
DMSO, water -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
