Cladribine, Adenosine deaminase inhibitor (ab142414)
Key features and details
- Nucleoside analogue that induces DNA double-strand breaks. Adenosine deaminase inhibitor
- CAS Number: 4291-63-8
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Cladribine, Adenosine deaminase inhibitor -
Description
Nucleoside analogue that induces DNA double-strand breaks. Adenosine deaminase inhibitor -
Biological description
Nucleoside analogue that induces DNA double-strand breaks. Adenosine deaminase inhibitor. Active in vivo and in vitro. Orally active. -
Purity
> 98% -
CAS Number
4291-63-8 -
Chemical structure
Properties
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Chemical name
(2R,3S,5R)-5-(6-Amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol -
Molecular weight
285.69 -
Molecular formula
C10H12ClN5O3 -
PubChem identifier
20279 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1C(C(OC1N2C=NC3=C2N=C(N=C3N)Cl)CO)O -
Source
Synthetic
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Research areas