1alpha-Hydroxyvitamin D3 (Alfacalcidol), Bone resorption inhibitor (ab142686)
Key features and details
- Bone resorption inhibitor. Metabolite of cholecalciferol.
- CAS Number: 41294-56-8
- Purity: > 98%
- Soluble in DMSO to 100 mM (with warming) and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
1alpha-Hydroxyvitamin D3 (Alfacalcidol), Bone resorption inhibitor -
Description
Bone resorption inhibitor. Metabolite of cholecalciferol. -
Alternative names
- Alfacalcidol
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Biological description
Metabolite of cholecalciferol (ab143594). Shows osteoprotective effects in vivo. Orally active. -
Purity
> 98% -
CAS Number
41294-56-8 -
Chemical structure
Properties
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Chemical name
(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-7a-Methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol -
Molecular weight
400.64 -
Molecular formula
C27H44O2 -
PubChem identifier
5282181 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM (with warming) and in ethanol to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)CCCC(C)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C -
Source
Synthetic
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Research areas
