ZM 241385, A2A antagonist (ab120218)
Key features and details
- Potent, selective A2A antagonist
- CAS Number: 139180-30-6
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 5 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
ZM 241385, A2A antagonist -
Description
Potent, selective A2A antagonist -
Biological description
Potent A2 adenosine receptor antagonist, with approx 50-fold selectivity for A2A receptors. (Ki values are 2A, A2B, A1 and A3 receptors, respectively). Orally active in vivo.
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Purity
> 99% -
CAS Number
139180-30-6 -
Chemical structure
Properties
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Chemical name
4-(2-[7-Amino-2-(2-furyl)[1,2,4]triazolo[2,3-a][1,3,5]triazin-5-ylamino]ethyl)phenol -
Molecular weight
337.34 -
Molecular formula
C16H15N7O2 -
PubChem identifier
176407 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 5 mM (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Oc1ccc(cc1)CCNc2nc(N)n3nc(nc3n2)c4ccco4 -
Source
Synthetic
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Research areas
