ZIP, protein kinase Mzeta (PKMzeta) inhibitor (ab120993)
Key features and details
- Novel, cell-permeable protein kinase Mζ (PKMζ) inhibitor
- CAS Number: 863987-12-6
- Purity: > 94%
- Soluble in water
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
ZIP, protein kinase Mzeta (PKMzeta) inhibitor -
Description
Novel, cell-permeable protein kinase Mζ (PKMζ) inhibitor -
Alternative names
- z-Pseudosubstrate inhibitory peptide
-
Biological description
Novel, cell-permeable PKMζ inhibitor, a constitutively active, atypical PKC isozyme. Efficacious in in vitro and in vivo models of synaptic plasticity (IC50 = 1 - 2.5 μM).
-
Purity
> 94% -
CAS Number
863987-12-6 -
Chemical structure
Properties
-
Molecular weight
1928.40 -
Molecular formula
C90H154N30O17 -
Sequence
SIYRRGARRWRKL (Modifications: N-terminal myristyl) -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
Source
Synthetic
-
Research areas
