WHI-P131 hydrochloride, JAK3 inhibitor (ab142126)
Key features and details
- JAK3 inhibitor
- CAS Number: 188829-39-2
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
WHI-P131 hydrochloride, JAK3 inhibitor -
Description
JAK3 inhibitor -
Alternative names
- JANEX-1
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Biological description
Cell-permeable Janus kinase 3 (JAK3) inhibitor (IC50 values of 9.1 µM and 78 µM for human and mouse recombinant proteins respectively). Selective versus JAK1, JAK2, SYK, BTK and LYN tyrosine kinases.
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Purity
> 98% -
CAS Number
188829-39-2 -
Chemical structure
Properties
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Chemical name
4-[(6,7-Dimethoxyquinazolin-4-yl)amino]phenol hydrochloride -
Molecular weight
333.78 -
Molecular formula
C16H15N3O3.HCl -
PubChem identifier
3794 -
Storage instructions
Shipped at room temperature. Store at -20°C. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)O)OC.Cl -
Source
Synthetic
