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Cancer Invasion/microenvironment Angiogenesis Angiogenic growth factors

Valsartan, Highly selective, , competitive AT1 receptor antagonist (ab141486)

Key features and details

  • Highly selective, potent, competitive AT1 receptor antagonist
  • CAS Number: 137862-53-4
  • Purity: > 98%
  • Soluble in DMSO to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    Valsartan, Highly selective, , competitive AT1 receptor antagonist
  • Description

    Highly selective, potent, competitive AT1 receptor antagonist
  • Biological description

    Highly selective, potent, competitive AT1 receptor antagonist (Ki = 2.38 nM). Shows antihypertensive effects in vivo. Shows central and peripheral effects. Orally active.
  • Purity

    > 98%
  • CAS Number

    137862-53-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2S)-3-Methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid
  • Molecular weight

    435.52
  • Molecular formula

    C24H29N5O3
  • PubChem identifier

    60846
  • Storage instructions

    Store at -20°C (desiccating conditions).
  • Solubility overview

    Soluble in DMSO to 100 mM
  • Handling

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)C(C(C)C)C(=O)O
  • Source

    Synthetic

  • Research areas

    • Cancer
    • Invasion/microenvironment
    • Angiogenesis
    • Angiogenic growth factors
    • Cardiovascular
    • Blood
    • Blood Pressure regulation
    • Cancer
    • Cancer Metabolism
    • Cellular metabolic process
    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Lipid metabolism
    • Biochemicals
    • Pharmacology
    • Signaling
    • Signal transduction
    • G-Protein related
    • Biochemicals
    • Pharmacology
    • Receptors & Transporters
    • Peptide Receptors
    • Angiotensin
    • AT2

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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