Urokinase type Plasminogen Activator Human Chromogenic Activity Assay Kit - Direct Assay (ab108916)
Key features and details
- Assay type: Enzyme activity (quantitative)
- Detection method: Colorimetric
- Platform: Microplate reader
- Sample type: Cell culture supernatant, Plasma
- Sensitivity: 0.062 IU/ml
Properties
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Storage instructions
Store at -20°C. Please refer to protocols. -
Components 96 tests Assay Diluent 1 x 30ml Human uPA Standard 1 vial Microplate 1 unit Sealing Tapes 3 units uPA Substrate 3 units -
Research areas
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Function
Specifically cleave the zymogen plasminogen to form the active enzyme plasmin. -
Tissue specificity
Expressed in the prostate gland and prostate cancers. -
Sequence similarities
Belongs to the peptidase S1 family.
Contains 1 EGF-like domain.
Contains 1 kringle domain.
Contains 1 peptidase S1 domain. -
Post-translational
modificationsPhosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding. -
Cellular localization
Secreted. - Information by UniProt
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Alternative names
- ATF
- ATF uPA
- BDPLT5
see all -
Database links
- Entrez Gene: 5328 Human
- Omim: 191840 Human
- SwissProt: P00749 Human
- Unigene: 77274 Human
Images
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Functional Studies - Urokinase type plasminogen activator Human Chromogenic Activity Assay Kit - Direct Assay (ab108916)uPA Chromogenic Activity Standard Curve (For Low uPA Activity Samples)
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Functional Studies - Urokinase type plasminogen activator Human Chromogenic Activity Assay Kit - Direct Assay (ab108916)uPA Chromogenic Activity Standard Curve (For High uPA Activity Samples)
