UBP141, GluN2D antagonist (ab120193)
Key features and details
- GluN2D (formerly NR2D) antagonist, with some subunit selectivity
- CAS Number: 344768-30-5
- Purity: > 98%
- Soluble in 2 eq. NaOH to 50 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
UBP141, GluN2D antagonist -
Description
GluN2D (formerly NR2D) antagonist, with some subunit selectivity -
Biological description
GluN2D (formerly NR2D) antagonist, displaying modest GluN2 (NR2) subunit selectivity. Shows 7-fold selectivity for GluN2D (NR2D)-containing NMDA receptors vs. GluN2B (NR2B) and 5-fold selectivity over GluN2A (NR2A ) but does not discriminate between GluN2C (NR2C) and GluN2D (NR2D). Ki values are 22 (NR1/2A), 17.2 (NR1/2B), 5.24 (NR1/2C) and 2.36 μM (NR1/2D).
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Purity
> 98% -
CAS Number
344768-30-5 -
Chemical structure
Properties
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Chemical name
(2R*,3S*)-1-(Phenanthrenyl-3-carbonyl)piperazine-2,3-dicarboxylic acid -
Molecular weight
378.38 -
Molecular formula
C21H18N2O5 -
PubChem identifier
85055269 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in 2 eq. NaOH to 50 mM (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(c1cc2c3ccccc3ccc2cc1)N4CCNC(C(=O)O)C4C(=O)O -
Source
Synthetic
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Research areas
