Tyrphostin 8, Tyrosine kinase inhibitor (ab141731)
Key features and details
- Tyrosine kinase inhibitor
- CAS Number: 3785-90-8
- Purity: > 98%
- Soluble in DMSO to 100 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Tyrphostin 8, Tyrosine kinase inhibitor -
Description
Tyrosine kinase inhibitor -
Biological description
Tyrosine kinase inhibitor. Inhibits EGFR tyrosine kinase activity (IC50 = 560 μM). Also inhibits calcineuin phosphatase activity (IC50 = 21 μM). Active in vivo and in vitro. -
Purity
> 98% -
CAS Number
3785-90-8 -
Chemical structure
Properties
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Chemical name
2-[(4-Hydroxyphenyl)methylidene]propanedinitrile -
Molecular weight
170.20 -
Molecular formula
C10H6N2O -
PubChem identifier
92970 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC(=CC=C1C=C(C#N)C#N)O -
Source
Synthetic
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Research areas
