TWS119, GSK-3beta inhibitor (ab142075)
Key features and details
- Potent cell-permeable GSK-3β inhibitor
- CAS Number: 601514-19-6
- Purity: > 95%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
TWS119, GSK-3beta inhibitor -
Description
Potent cell-permeable GSK-3β inhibitor -
Biological description
Potent cell-permeable GSK-3β inhibitor (IC50 = 30 nM). Induces stem cell neurogenesis in vitro. -
Purity
> 95% -
CAS Number
601514-19-6 -
Chemical structure
Properties
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Chemical name
3-[[6-(3-Aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenol -
Molecular weight
318.33 -
Molecular formula
C18H14N4O2 -
PubChem identifier
9549289 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC(=CC(=C1)N)C2=CC3=C(N2)N=CN=C3OC4=CC=CC(=C4)O -
Source
Synthetic
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Research areas
