Tenovin-1, p53 Activator (ab120889)
Key features and details
- p53 Activator
- CAS Number: 380315-80-0
- Purity: > 98%
- Soluble in DMSO to 0.25 mg/ml
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Tenovin-1, p53 Activator -
Description
p53 Activator -
Biological description
p53 Activator. Protects p53 from MDM2 mediated degradation through SirT1 inhibition. Inhibits downstream histone acetylation, activates p21CIP/WAF1. Potent antiproliferative effects in vitro. -
Purity
> 98% -
CAS Number
380315-80-0 -
Chemical structure
Properties
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Chemical name
N-[[[4-(Acetylamino)phenyl]amino]thioxomethyl-4-(1,1-dimethylethyl)]benzamide -
Molecular weight
369.48 -
Molecular formula
C20H23N3O2S -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 0.25 mg/ml -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(=O)Nc1ccc(cc1)NC(=S)NC(=O)c1ccc(cc1)C(C)(C)C -
Source
Synthetic
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Research areas