SR 27897 (Lintitript), CCK1 receptor antagonist (ab142813)
Key features and details
- Highly potent, selective, competitive, non-peptide CCK1 receptor antagonist
- CAS Number: 136381-85-6
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SR 27897 (Lintitript), CCK1 receptor antagonist -
Description
Highly potent, selective, competitive, non-peptide CCK1 receptor antagonist -
Biological description
Highly potent, selective, competitive, non-peptide CCK1 receptor antagonist (Ki = 0.2 nM). Increases plasma leptin levels. Shows central effects. Stimulates food intake in vivo. Orally active.
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Purity
> 98% -
CAS Number
136381-85-6 -
Chemical structure
Properties
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Chemical name
2-[[[4-(2-Chlorophenyl)-2-thiazolyl]amino]carbonyl]-1H-indole-1-acetic acid -
Molecular weight
411.86 -
Molecular formula
C20H14ClN3O3S -
PubChem identifier
122077 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(Nc1nc(cs1)c2ccccc2Cl)c4cc3ccccc3n4CC(=O)O -
Source
Synthetic
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Research areas
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Vitamin D Receptor
- Epigenetics and Nuclear Signaling
- Nuclear Signaling Pathways
- Nuclear Receptors
- Orphan Nuclear Receptors
