SQ 22536, Non-competitive adenylyl cyclase inhibitor (ab120642)
Key features and details
- Non-competitive adenylyl cyclase inhibitor
- CAS Number: 17318-31-9
- Purity: > 99%
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
SQ 22536, Non-competitive adenylyl cyclase inhibitor -
Description
Non-competitive adenylyl cyclase inhibitor -
Biological description
Non-competitive adenylyl cyclase inhibitor. Inhibits catecholamine stimulated cAMP production (IC50 values are 0.08-1.45 and 0.08-0.27 mM in catfish and rat hepatocyte cell membranes, respectively). Inhibits muscarinic Ca2+ signalling in rat carotid bodies in vitro.
-
Purity
> 99% -
General notes
This compound appears to be unstable in strongly acidic solutions. We therefore recommend avoiding exposure to low pH.
-
CAS Number
17318-31-9 -
Chemical structure
Properties
-
Chemical name
9-(Tetrahydro-2-furanyl)-9H-purin-6-amine -
Molecular weight
205.22 -
Molecular formula
C9H11N5O -
PubChem identifier
5270 -
Storage instructions
Store at +4°C. Please see notes section. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
C1CC(OC1)N2C=NC3=C(N=CN=C32)N -
Source
Synthetic
-
Research areas
- Biochemicals
- Pharmacology
- Signaling
- Signal transduction
- Inositol & cAMP signaling
- Adenylyl cyclase
- Activators
- Biochemicals
- Research Area
- Heart disease
- Signaling
- Inositol & cAMP signaling
- Adenylyl cyclase
- Activators
- Biochemicals
- Research Area
- Pain & inflammation
- Signaling
- Inositol & cAMP signaling
- Adenylyl cyclase
- Activators
- Biochemicals
- Research Area
- Alzheimer's Disease
- Signaling
- Signal transduction
- Inositol & cAMP signaling
- Adenylyl cyclase
- Activators
- Biochemicals
- Research Area
- Diabetes
- Signaling
- Signal transduction
- Inositol & cAMP signaling
- Adenylyl cyclase
- Activators
- Biochemicals
- Research Area
- Hypertension
- Signaling
- Signal transduction
- Inositol & cAMP signaling
- Adenylyl cyclase
- Activators
- Biochemicals
- Research Area
- Obesity
- Signaling
- Signal transduction
- Inositol & cAMP signaling
- Adenylyl cyclase
- Activators
- Biochemicals
- Research Area
- Respiratory disease
- Signaling
- Inositol & cAMP signaling
- Adenylyl cyclase
- Activators