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Somatostatin Receptor 2 peptide (ab218996)

Description

Preparation and Storage

  • Alternative names

    • Somatostatin receptor type 2
    • SRIF-1
    • SRIF1
    • SS-2-R
    • SS2-R
    • SS2R
    • SSR2_HUMAN
    • SST2
    • SSTR2
    see all

  • Function

    Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels.

  • Tissue specificity

    Cerebrum and kidney. In lesser amounts in jejunum, colon and liver.

  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.

  • Cellular localization

    Cell membrane.
  • Information by UniProt

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