Antibodies, Proteins, Kits and Reagents for Life Science

Key features and details

Suitable for: Blocking

Product name

Somatostatin Receptor 2 peptide
See all Somatostatin Receptor 2 proteins and peptides
Animal free

No
Nature

Synthetic

Alternative names
- Somatostatin receptor type 2
- SRIF-1
- SRIF1
- SS-2-R
- SS2-R
- SS2R
- SSR2_HUMAN
- SST2
- SSTR2
see all
Function

Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels.
Tissue specificity

Cerebrum and kidney. In lesser amounts in jejunum, colon and liver.
Sequence similarities

Belongs to the G-protein coupled receptor 1 family.
Cellular localization

Cell membrane.
Target information above from: UniProt accession P30874 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

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