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Neuroscience Neurotransmission Intracellular Signaling Kinases

SKF 83566 hydrobromide, D1 receptor antagonist (ab141146)

Price and availability

231 177 ₸

Availability

Order now and get it on Friday February 26, 2021

Key features and details

  • Potent, selective D1 receptor antagonist
  • CAS Number: 108179-91-5
  • Purity: > 99%
  • Soluble in water to 5 mM, in ethanol to 25 mM and in DMSO to 100 mM
  • Form / State: Solid
  • Source: Synthetic

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Overview

  • Product name

    SKF 83566 hydrobromide, D1 receptor antagonist
  • Description

    Potent, selective D1 receptor antagonist
  • Biological description

    Potent, selective D1 receptor antagonist (Ki = 0.4 nM). Centrally active following systemic administration. Various neurological effects in vitro and in vivo.

  • Purity

    > 99%
  • CAS Number

    108179-91-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    8-Bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol hydrobromide
  • Molecular weight

    413.15
  • Molecular formula

    C17H18BrNO.HBr
  • PubChem identifier

    23581817
  • Storage instructions

    Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 5 mM, in ethanol to 25 mM and in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Refer to SDS for further instruction.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    Br.Brc1cc2CCN(C)CC(c2cc1O)c3ccccc3
  • Source

    Synthetic

  • Research areas

    • Neuroscience
    • Neurotransmission
    • Intracellular Signaling
    • Kinases
    • Signal Transduction
    • Protein Phosphorylation
    • Ser / Thr Kinases
    • MAPK Pathway
    • Stem Cells
    • Signaling Pathways
    • TGF beta
    • Cytoplasmic

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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