SD 169, ATP-competitive p38alpha MAPK inhibitor (ab120836)
Key features and details
- Potent, selective and ATP-competitive p38α MAPK inhibitor
- CAS Number: 1670-87-7
- Purity: > 99%
- Soluble in water to 5 mM, in ethanol to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SD 169, ATP-competitive p38alpha MAPK inhibitor -
Description
Potent, selective and ATP-competitive p38α MAPK inhibitor -
Biological description
Potent, selective and ATP-competitive p38α MAPK inhibitor (IC50 values are 3.2 and 122 nM for α and β, respectively). Orally active. Promotes axonal regeneration in vivo.
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Purity
> 99% -
CAS Number
1670-87-7 -
Chemical structure
Properties
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Chemical name
Indole-5-carboxamide -
Molecular weight
160.18 -
Molecular formula
C9H8N2O -
PubChem identifier
14973220 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 5 mM, in ethanol to 100 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
NC(=O)c1cc2ccnc2cc1 -
Source
Synthetic
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Research areas
