SC-1 (Pluripotin), Dual kinase and GTPase inhibitor (ab144425)
Key features and details
- Dual kinase (ERK1, MAPK3) and GTPase inhibitor
- CAS Number: 839707-37-8
- Purity: > 98%
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
SC-1 (Pluripotin), Dual kinase and GTPase inhibitor -
Description
Dual kinase (ERK1, MAPK3) and GTPase inhibitor -
Biological description
Dual kinase (ERK1, MAPK3) and GTPase inhibitor. Activates stem cell renewal. Enables propagation of undifferentiated murine ESCs in the absence of leukemia inhibitory factor. -
Purity
> 98% -
CAS Number
839707-37-8 -
Chemical structure
Properties
-
Chemical name
N-(3-(7-(1,3-Dimethyl-1H-pyrazol-5-ylamino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide -
Molecular weight
550.54 -
Molecular formula
C27H25F3N8O2 -
PubChem identifier
12003241 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)N3CC4=CN=C(N=C4N(C3=O)C)NC5=CC(=NN5C)C -
Source
Synthetic
-
Research areas