SB 271046 hydrochloride, 5-HT6 antagonist (ab120589)
Key features and details
- Potent, selective 5-HT6 antagonist
- CAS Number: 209481-24-3
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 5 mM (with heating)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SB 271046 hydrochloride, 5-HT6 antagonist -
Description
Potent, selective 5-HT6 antagonist -
Biological description
Potent and selective 5-HT6 receptor antagonist (Ki = 1-2 nM). Displays >200-fold selectivity for 5-HT6 receptors (vs. other receptor binding sites and ion channels). Poor penetration of the blood-brain barrier. Nootropic effects in vivo.
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Purity
> 99% -
CAS Number
209481-24-3 -
Chemical structure
Properties
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Chemical name
5-Chloro-N-[4-methoxy-3-(1-piperazinyl)phenyl]-3-methylbenzo[b]thiophen-2-sulfonamide hydrochloride -
Molecular weight
488.45 -
Molecular formula
C20H22CIN3O3S2.HCl -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 5 mM (with heating) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
