SATA (N-Succinimidyl-S-acetylthioacetate), Protein modification thiolating reagent (ab145622)
Key features and details
- Primary amine-reactive protein modification thiolating reagent
- CAS Number: 76931-93-6
- Purity: > 94%
- Soluble in DMSO to 4 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SATA (N-Succinimidyl-S-acetylthioacetate), Protein modification thiolating reagent -
Description
Primary amine-reactive protein modification thiolating reagent -
Biological description
Primary amine-reactive protein modification thiolating reagent. Adds protected sulfhydryls to targeted proteins. Induces stable recombinant TNF-α trimer formation by formation of disulfide bridges between reactive thiol groups on adjacent TNF-α molecules, which show increased therapeutic efficacy in vivo. -
Purity
> 94% -
CAS Number
76931-93-6 -
Chemical structure
Properties
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Chemical name
(2,5-Dioxopyrrolidin-1-yl) 2-acetylsulfanylacetate -
Molecular weight
231.23 -
Molecular formula
C8H9NOS -
PubChem identifier
127532 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 4 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(=O)SCC(=O)ON1C(=O)CCC1=O -
Source
Synthetic
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Research areas
