Nargenicin A1, Antibiotic agent (ab144312)
Key features and details
- Broad spectrum antibiotic agent. Potential anti-inflammatory agent.
- CAS Number: 70695-02-2
- Purity: > 98%
Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Actinomyces sp.
Overview
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Product name
Nargenicin A1, Antibiotic agent -
Description
Broad spectrum antibiotic agent. Potential anti-inflammatory agent. -
Biological description
Broad spectrum antibiotic agent. Potential anti-inflammatory agent. Active against Gram-positive bacteria, particularly Staphylococcus and Clostridia. Attenuates LPS-induced nitric oxide production in microglia. Suppresses IL-1β, TNF-α and iNOS production.
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Purity
> 98% -
CAS Number
70695-02-2 -
Chemical structure
Properties
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Chemical name
(3S,4R,5R,6R,7S,8R,11S,13S,16S,17R,18E)-6-Hydroxy-16-[(1R)-1-hydroxyethyl]-13-methoxy-5,17,19-trimethyl-14-oxo-2,15-dioxatetracyclo[9.8.0.01,7.03,8]nonadeca-9,18-dien-4-yl-1H-pyrrole-2-carboxylate
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Molecular weight
515.60 -
Molecular formula
C28H37NO8 -
PubChem identifier
6326334 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C[C@@H]1/C=C(/[C@]23[C@@H](C[C@@H](C(=O)O[C@@H]1[C@@H](C)O)OC)C=C[C@@H]4[C@H]2[C@@H]([C@H]([C@H]([C@@H]4O3)OC(=O)C5=CC=CN5)C)O)\C -
Source
Actinomyces sp.
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Research areas
