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Biochemicals Product Range New

Carnosol, Antioxidant, and anticancer agent (ab142848)

Key features and details

  • Anti-oxidant, and anticancer agent
  • CAS Number: 5957-80-2
  • Purity: > 98%
  • Soluble in DMSO and in ethanol
  • Form / State: Solid
  • Source: Rosemarinus officinalis

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Overview

  • Product name

    Carnosol, Antioxidant, and anticancer agent
  • Description

    Anti-oxidant, and anticancer agent
  • Biological description

    Anti-oxidant and anticancer agent (IC50 values are 9 and 82 μM for LPS-stimulated NO production and MCF-7 cellsrespectively). Inhibits NFκB and COX-2 induction. Targets PI3K/Akt and apoptotic related proteins. ERα and ARα antagonist. Shows antitumor effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    5957-80-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    10,20-Dihydroxy-7,10-(epoxymethano)abiet-8,11,13-triene-20-one
  • Molecular weight

    330.42
  • Molecular formula

    C20H26O4
  • PubChem identifier

    2579
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO and in ethanol
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(C)C1=C(C(=C2C(=C1)C3CC4C2(CCCC4(C)C)C(=O)O3)O)O
  • Source

    Rosemarinus officinalis

  • Research areas

    • Biochemicals
    • Product Range
    • New
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Signaling
    • Signal transduction
    • Nitric oxide & oxidative stress
    • Antioxidants
    • Biochemicals
    • Pharmacology
    • Signaling
    • Signal transduction
    • Cytokines, NF-κB & IκB signaling
    • Biochemicals
    • Pharmacology
    • Signaling
    • Signal transduction
    • PI3K/Akt signaling
    • Inhibitors

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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